PhD candidate in Molecular Cell Biology

Faculty of Science – Swammerdam Institute for Life Sciences

19 april 2017
Master's degree
€2,191 to €2,801 gross per month
17 mei 2017
38 hours per week

The Swammerdam Institute for Life Sciences (SILS) is one of the largest institutes of the Faculty of Science. Its approximately 240 scientists and staff members work in 16 research groups that perform excellent research centered on three themes:

  1. Cell & Systems Biology;
  2. Neurosciences, and
  3. Molecular Life Sciences.

The research performed in the section Molecular Cytology focusses on 'Self-organization and signaling in living cells'. In this context we are seeking for an enthusiastic and talented PhD candidate who likes to work in a multi-disciplinary team of scientists.

Project description

The research project aims at engineering novel genetically encoded fluorescent probes with lifetime contrast that can be used for functional imaging of cellular processes. This project builds on our extensive experience in the field of fluorescent protein engineering, signal transduction and functional imaging. Due to recent developments in imaging technology it is possible to obtain fluorescence lifetime maps with high temporal resolution. This enables true quantitative imaging of molecular processes in living cells. To expand the application of this technology, we will generate a new class of genetically encoded fluorescent probes that display lifetime contrast.

The proposed project involves biochemistry (protein purification, spectroscopic characterization), molecular biology (cloning, generation of DNA libraries), eukaryotic cell culture, fluorescent biosensor engineering, high content in vivo screening and advanced microscopy.

The project is funded by a grant from the Netherlands Organization for Scientific Research (NWO).


Candidates should have a Master’s degree in Biochemistry, Cell biology, or Medical biology (or equivalent), have excellent communication skills and be highly motivated to conduct fundamental scientific research in a team of enthusiastic scientists. Experience with fluorescence microscopy, or protein engineering is a plus.

Further information

Project information may be obtained from:


The appointment will be on a temporary basis for a period of 4 years (initial appointment will be for a period of 18 months and after satisfactory evaluation it can be extended for a total duration of 4 years) and should lead to a dissertation (PhD thesis). An educational plan will be drafted that includes attendance of courses and (international) meetings. The PhD candidate is also expected to assist in teaching of undergraduates.

Based on a full-time appointment (38 hours per week) the gross monthly salary will range from €2,191 in the first year to €2,801 in the last year. The Collective Labour Agreement for Dutch Universities is applicable.

Job application

Due to limitations in recruitment budget we will only consider candidates that are currently in Europe. Please do not respond if you are not in Europe.

Applications may only be submitted by electronic mail and should be sent to: To enable us to process your application immediately, please quote the vacancy number 17-199 and the position you are applying for in the subject-line.

Applications must include a curriculum vitae and a letter of motivation. Please combine these documents in one single attachment and also mention the months (not just years) in your CV when referring to your education and work experience.

Applications will be accepted until 17 May 2017. #LI-DNP

No agencies please

Gepubliceerd door  Universiteit van Amsterdam